African American men are disproportionately affected by prostate cancer, with a mortality rate that is 2.4 times higher than that of white men. This disparity is due in part to genetic factors, as family history has been linked to an increased risk of prostate cancer in African American men.

Studies have shown that African American men with a first-degree relative (parent, sibling, or child) diagnosed with prostate cancer are at a higher risk for developing the disease than white men with the same family history. Additionally, the risk of developing prostate cancer increases with the number of affected family members. Having two or more affected family members has been associated with a two-fold increase in risk.

The same studies have also shown that African American men with a family history of prostate cancer are at an increased risk of developing aggressive forms of the disease. This means that they are more likely to develop tumors that are more difficult to treat and have a greater risk of metastasizing.

It is important for African American men to be aware of their family history of prostate cancer and to discuss it with their doctor. Those with a family history should discuss the potential benefits of testing and early detection with their doctor and should make sure to get regular screenings. In addition, African American men should